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Ribostamycin sulfate
Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.
Catalog No. T1214Cas No. 53797-35-6
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Purity:99.57%
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Ribostamycin sulfate
Catalog No. T1214Cas No. 53797-35-6
Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $31 | In Stock | |
| 25 mg | $48 | In Stock | |
| 50 mg | $65 | In Stock | |
| 100 mg | $97 | In Stock | |
| 200 mg | $155 | In Stock | |
| 500 mg | $262 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome. |
| In vitro | Compared to other antibiotics, Ribostamycin (400 mg/kg/day) exhibits the lowest ototoxicity and maintains lower drug concentrations in the inner ear fluid of guinea pigs. Ribostamycin demonstrates minimal ototoxicity to both the cochlea and vestibular apparatus in guinea pigs. |
| In vivo | Ribostamycin effectively inhibits aminoglycoside-modifying enzymes in gentamicin-resistant Pseudomonas aeruginosa without suppressing protein disulfide isomerase (PDI) activity, although it does inhibit its chaperone activity. At a 100:1 molar ratio with PDI, Ribostamycin nearly completely inhibits chaperone activity. The dissociation constant (KD) for Ribostamycin binding to immunogenic PDI is 0.319 mM. Additionally, Ribostamycin exhibits antibacterial activity against Borrelia burgdorferi with a minimum inhibitory concentration (MIC) of 18.7 mg/L. At a concentration of 16 mcg/mL, Ribostamycin inhibits P. stagnora, P. zopfii, and P. wickerhamii strains by 100%, 100%, and 95%, respectively. |
| Alias | Vistamycin sulfate |
| Molecular Weight | 552.55 |
| Formula | C17H34N4O10·H2SO4 |
| Cas No. | 53797-35-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: Insoluble H2O: 10 mM | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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